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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF6
All Species:
18.48
Human Site:
Y195
Identified Species:
58.1
UniProt:
Q8IWS0
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWS0
NP_001015877.1
365
41290
Y195
D
E
M
E
S
S
S
Y
R
D
R
S
P
H
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852628
365
41256
Y195
D
E
M
E
S
S
S
Y
R
D
R
S
P
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4J7
364
41121
Y195
D
E
M
E
S
S
S
Y
R
D
R
S
P
H
R
Rat
Rattus norvegicus
Q5I0E2
336
37196
K184
K
M
K
F
S
R
F
K
R
L
M
K
E
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511831
365
40968
Y195
D
E
I
E
S
S
S
Y
R
D
R
S
P
H
R
Chicken
Gallus gallus
XP_420223
366
41075
S195
T
D
E
I
E
S
S
S
Y
R
D
R
S
P
H
Frog
Xenopus laevis
NP_001088235
366
40929
S196
E
E
T
E
S
S
S
S
R
D
R
S
P
H
R
Zebra Danio
Brachydanio rerio
NP_956059
363
40321
D205
P
L
R
G
S
P
G
D
S
G
L
R
C
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.7
N.A.
97.2
21.1
N.A.
94.5
89.3
75.4
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
100
N.A.
98.6
38.6
N.A.
95.6
94.2
85.5
82.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
13.3
N.A.
93.3
13.3
80
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
13.3
N.A.
100
20
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% C
% Asp:
50
13
0
0
0
0
0
13
0
63
13
0
0
0
0
% D
% Glu:
13
63
13
63
13
0
0
0
0
0
0
0
13
13
0
% E
% Phe:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
13
% F
% Gly:
0
0
0
13
0
0
13
0
0
13
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
13
% H
% Ile:
0
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
13
0
0
0
0
13
0
0
0
13
0
0
0
% K
% Leu:
0
13
0
0
0
0
0
0
0
13
13
0
0
0
0
% L
% Met:
0
13
38
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
13
0
0
0
0
0
0
63
13
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
13
0
0
75
13
63
25
0
0
63
% R
% Ser:
0
0
0
0
88
75
75
25
13
0
0
63
13
0
0
% S
% Thr:
13
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _